The Global Flow Chemistry Market is expected to grow from USD 1.55 Bn in 2020 to USD 2.85 Bn by 2027, at a CAGR of 10.7%.
Increasing demand for flow chemistry in biopharmaceutical applications is anticipated to drive the market growth in the near future. To meet the needs of a competitive medication sector, pharmaceutical companies have been recently driven to explore new ways to supply more efficient technologies. For example, in order to complete its toolbox, Seqens (France) lab is anticipated be equipped at mid-2021 with a new GMP pilot plant, capable of hosting nitration, diazotization or halogenation type reactions, and producing representative pre-commercial batches up to the ton scale. As a result, the significance of process chemistry and scale-up has never been more highlighted. Future medicinal chemistry may use flow chemistry to optimize drug development, the potential regulatory and environmental challenges that this poses, and whether the academic and industrial sectors would benefit from a more harmonized system related to flow chemistry market.
Additionally, the discovery and development of green chemistry in flow has a lot of potential. The competition to develop more efficient catalysts, synthetic techniques that use renewable feedstocks, reduce chemical waste, and identify reaction pathways that demand softer temperatures is more crucial nowadays. Solvent-free synthesis, for example, has emerged as a green chemistry prospect, but it is a risk-reward trade-off in its engineering. In the absence of a solvent, reaction speeds can be increased, and separations can be eliminated, which is a huge step in and of itself. In solvent-free systems, however, reaction products and by-products can precipitate, clogging or fouling equipment.
Based on reactor type, the CSTR segment is anticipated to hold the largest market share during the forecast period as it continuously feeds and exhausts reactants. CSTR reactors feature good mixing and function well in steady-state conditions with consistent characteristics. Several Continuous Stirred Tank Reactors (CSTRs) can be linked together to form a cascade in instances when a reaction is too sluggish or when two Fraunhofer IMMFraunhofer FRAUNHOFER IMMiscible or viscous liquids require a high agitation rate. For instance, among other applications in the chemical and pharmaceutical industry, 3D Printing technique has been used to produce affordable reaction ware. In recent years, 3D Printing has been applied in flow chemistry technology. Additionally, its used in the chemical and pharmaceutical sector as it is economical to manufacture intricate continuous flow components and systems.
In terms of geography, North America is expected to dominate the flow chemistry market during the forecast period owing to its investments in research in the industry. For instance, in 2018, the Canadian government has introduced fresh opportunities to renew and modernize its Chemicals Management Plan (CMP) and was also in the process of reviewing the Canadian Environmental Protection Act, 1999 (CEPA 1999). CEPA 1999 and CMP are foundational elements of Canada’s approach for managing chemicals The continuous flow synthesis laboratory at the Université de Montréal allows scientists to carry out multi-step syntheses that were previously done in discrete batch processes at scales ranging from mg to 100's of grams, removing some of the safety concerns associated with batch scale up.
Moreover, North America accounted for the largest market share in flow chemistry market. Government measures aimed at reducing pollution are projected to boost the use of efficient and green technologies in the economy in the near future. For instance, “The Clean Air Act” in the US states Under the Act, EPA seeks to provide industry with flexibility on ways to control emissions while maintaining accountability for achieving reductions. In the future years, increased chemical and pharmaceutical manufacturing, as well as increased investment by petrochemical producers, are expected to drive regional market demand.
The key players operating in the flow chemistry market are: